Congenital cataracts: gene mapping

Hum Genet. 2000 Jan;106(1):1-13. doi: 10.1007/s004390051002.


Congenital cataracts are one of the major causes of induced blindness in children. Gene mapping is an important step in understanding the molecular defects of congenital cataracts. Some congenital cataract genes have been mapped, and more genes will be located and identified in the future. The locations and candidate locations of congenital cataract genes are discussed in this review.

Publication types

  • Review

MeSH terms

  • Animals
  • Cataract / congenital*
  • Cataract / genetics*
  • Cell Membrane / metabolism
  • Chromosome Aberrations
  • Chromosome Mapping
  • Crystallins / biosynthesis
  • Cytoskeleton / metabolism
  • Genetic Linkage
  • Humans
  • Mice
  • Models, Genetic
  • Receptors, Retinoic Acid / biosynthesis
  • Syndrome


  • Crystallins
  • Receptors, Retinoic Acid
  • retinoic acid binding protein I, cellular