Urol Clin North Am. 2000 Aug;27(3):383-92, vii. doi: 10.1016/s0094-0143(05)70087-2.


Neuroblastoma is a malignant tumor of neural crest origin that may arise anywhere along the sympathetic ganglia or within the adrenal medulla. The median age of diagnosis is 2 years; however occurrence is skewed toward younger children, with nearly 35% of cases occurring under 1 year of age and the remainder under 10 years of age. Seventy-five percent of neuroblastomas originate within the abdomen or pelvis, and half of these occur within the adrenal medulla, whereas 20% originate within the posterior mediastinum and 5% within the neck.

Publication types

  • Review

MeSH terms

  • Child
  • Cytogenetics
  • Humans
  • Neuroblastoma* / diagnosis
  • Neuroblastoma* / mortality
  • Neuroblastoma* / therapy
  • Prognosis
  • Survival Rate
  • Tomography, X-Ray Computed