Stem cells: You make me feel so glial

Curr Biol. 2000 Aug 24;10(16):R595-7. doi: 10.1016/s0960-9822(00)00636-9.

Abstract

The signals that instruct neural stem cells to differentiate into glia have long proved elusive. Surprising new evidence suggests that this role could be fulfilled by Notch signalling, previously thought to be a general inhibitor of stem cell differentiation.

MeSH terms

  • Animals
  • Cell Differentiation*
  • Membrane Proteins / metabolism
  • Neuroglia / physiology*
  • Receptors, Notch
  • Receptors, Opioid, delta / metabolism
  • Signal Transduction / physiology*
  • Stem Cells / physiology*

Substances

  • Membrane Proteins
  • Receptors, Notch
  • Receptors, Opioid, delta