Infection, inflammation and the risk of cerebral palsy

Curr Opin Neurol. 2000 Apr;13(2):133-9. doi: 10.1097/00019052-200004000-00004.


The balance of current evidence indicates that intrauterine exposure to infection and inflammation contributes to the risk of cerebral palsy. The mechanisms involved are not well understood and may differ in very immature versus term infants. Term infants exposed to maternal infection are predisposed to delivery room depression and neonatal encephalopathy.

Publication types

  • Review

MeSH terms

  • Cerebral Palsy / diagnosis
  • Cerebral Palsy / etiology*
  • Cerebral Palsy / genetics
  • Cerebral Palsy / microbiology
  • Fetal Diseases*
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / diagnosis
  • Infections / complications*
  • Infections / embryology*
  • Inflammation / complications*
  • Inflammation / embryology*
  • Risk Factors