Plasmid-mediated florfenicol resistance encoded by the floR gene in Escherichia coli isolated from cattle

A Cloeckaert; S Baucheron; G Flaujac; S Schwarz; C Kehrenberg; J L Martel; E Chaslus-Dancla

doi:10.1128/AAC.44.10.2858-2860.2000

Plasmid-mediated florfenicol resistance encoded by the floR gene in Escherichia coli isolated from cattle

Antimicrob Agents Chemother. 2000 Oct;44(10):2858-60. doi: 10.1128/AAC.44.10.2858-2860.2000.

Authors

A Cloeckaert¹, S Baucheron, G Flaujac, S Schwarz, C Kehrenberg, J L Martel, E Chaslus-Dancla

Affiliation

¹ Station de Pathologie Aviaire et Parasitologie, Institut National de la Recherche Agronomique, 37380 Nouzilly, France. cloeckae@tours.inra.fr

Abstract

A florfenicol resistance gene almost identical to floR of Salmonella enterica serovar Typhimurium DT104 was detected on 110- to 125-kb plasmids in Escherichia coli isolates of animal origin. Analysis of the floR gene flanking regions of one of the plasmids showed that they were different from those encountered in S. enterica serovar Typhimurium DT104.

MeSH terms

Animals
Cattle
Cattle Diseases / microbiology*
Dogs
Drug Resistance, Microbial
Escherichia coli / enzymology*
Escherichia coli / genetics*
Escherichia coli Infections / microbiology*
Escherichia coli Infections / veterinary*
Genes, Bacterial / genetics*
Molecular Sequence Data
Plasmids / genetics*
Reverse Transcriptase Polymerase Chain Reaction
Sheep
Thiamphenicol / analogs & derivatives*
Thiamphenicol / pharmacology

Substances

florfenicol
Thiamphenicol

Associated data

GENBANK/AF231986