Eosinophilic angiocentric fibrosis

J Laryngol Otol. 2000 Jul;114(7):563-4. doi: 10.1258/0022215001906183.


Eosinophilic angiocentric fibrosis (EAF) is a rare inflammatory fibrosing condition of unknown aetiology that involves the nose or larynx producing mucosal thickening and severe obstructive symptoms. We report the first case affecting a male. He presented with nasal obstruction requiring septoplasty. The clinical and histopathological features of the condition are discussed and a comparison is made with the seven previous reported cases.

Publication types

  • Case Reports

MeSH terms

  • Eosinophilia / complications*
  • Eosinophilia / surgery
  • Fibrosis
  • Humans
  • Male
  • Middle Aged
  • Nasal Obstruction / etiology*
  • Nasal Obstruction / surgery
  • Nasal Septum / pathology*
  • Nasal Septum / surgery