[Melanin complex of the fungus Inonotus obliquus]

Prikl Biokhim Mikrobiol. Jul-Aug 2000;36(4):439-44.
[Article in Russian]

Abstract

The fungus Inonotus obliquus (Pers.) Pil. synthesised high-molecular-weight phenolic pigments that were assigned to melanins according to their physicochemical properties. It was showed that copper ions (0.008%), pyrocatechol (1.0 mM), and tyrosine (20.0 mM) stimulated the melanogenesis. The production of melanin correlated with the synthesis of o- and p-diphenoloxidases. The fungal melanin had strong antioxidant and genoprotective effects.

Publication types

  • English Abstract

MeSH terms

  • Antimutagenic Agents / pharmacology
  • Antioxidants / pharmacology
  • Basidiomycota / drug effects
  • Basidiomycota / metabolism*
  • Catechols / pharmacology
  • Copper / pharmacology
  • Melanins / biosynthesis
  • Melanins / metabolism*
  • Melanins / pharmacology
  • Tyrosine / pharmacology

Substances

  • Antimutagenic Agents
  • Antioxidants
  • Catechols
  • Melanins
  • Tyrosine
  • Copper
  • catechol