Thrombotic thrombocytopenic purpura: MRI demonstration of persistent small cerebral infarcts after clinical recovery

Neuroradiology. 2000 Aug;42(8):616-8. doi: 10.1007/s002340000348.


Abnormalities in the brain of patients with thrombotic thrombocytopenic purpura (TTP) are infrequent on MRI, often reversible and mainly limited to symptomatic stages of the disease. We report a case in which high-resolution MRI demonstrated multiple persistent small cortical infarcts after clinical remission. High-resolution MRI investigations may detect clinically latent but permanent brain damage, and complement clinical judgement in guiding therapeutic decisions.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebral Infarction / complications
  • Cerebral Infarction / pathology*
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Purpura, Thrombotic Thrombocytopenic / complications
  • Purpura, Thrombotic Thrombocytopenic / pathology*