Nitrogenase: standing at the crossroads

Curr Opin Chem Biol. 2000 Oct;4(5):559-66. doi: 10.1016/s1367-5931(00)00132-0.

Abstract

Nitrogenase catalyzes the ATP-dependent reduction of dinitrogen to ammonia, which is central to the process of biological nitrogen fixation. Recent progress towards establishing the mechanism of action of this complex metalloenzyme reflects the contributions of a combination of structural, biochemical, spectroscopic, synthetic and theoretical approaches to a challenging problem with implications for a range of biochemical and chemical systems.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Catalysis
  • Kinetics
  • Nitrogenase / metabolism*
  • Oxidation-Reduction

Substances

  • Adenosine Triphosphate
  • Nitrogenase