Chemokines and their receptors in allograft rejection

Curr Opin Immunol. 2000 Oct;12(5):511-6. doi: 10.1016/s0952-7915(00)00130-8.


Despite current recognition of over 40 chemokines and more than 18 chemokine receptors, understanding of their role in transplant immunobiology and transplant rejection is extremely limited and fragmentary. Recent literature has demonstrated the presence of chemokines and their receptors in transplants and some studies demonstrate important functional roles.

Publication types

  • Review

MeSH terms

  • Animals
  • Chemokines / physiology*
  • Chemotaxis, Leukocyte
  • Graft Rejection*
  • Humans
  • Kidney Transplantation
  • Neutrophils / immunology
  • Receptors, Chemokine / physiology*
  • Reperfusion Injury / complications
  • Transplantation, Homologous


  • Chemokines
  • Receptors, Chemokine