Dendritic cells and prospects for transplantation tolerance

Curr Opin Immunol. 2000 Oct;12(5):528-35. doi: 10.1016/s0952-7915(00)00134-5.


The past year has witnessed the resolution of some long-standing enigmas surrounding the immunobiology of dendritic cells, illuminating their opposing roles in peripheral tolerance and allograft rejection. Nevertheless these advances have posed many new questions, the answers to which may subtly influence our approach to the treatment of rejection while bringing ever closer the prospect of donor-specific transplanation tolerance.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Differentiation
  • Dendritic Cells / physiology*
  • Humans
  • Stem Cells / physiology
  • Transplantation Tolerance*