Posterior capsule opacification 3 years after implantation of an AcrySof and a MemoryLens in fellow eyes

J Cataract Refract Surg. 2000 Aug;26(8):1176-82. doi: 10.1016/s0886-3350(00)00583-6.


Purpose: To compare the rates of lens epithelial cell (LEC) migration and posterior capsule opacification (PCO) 1 and 3 years after sutureless small incision phacoemulsification and in-the-bag implantation of 2 acrylic polymer intraocular lenses (IOLs)-the AcrySof and MemoryLens-in fellow eyes of patients.

Setting: Eye Clinic, Beyoğlu Education and Research Hospital, Istanbul, Turkey.

Methods: Fifty patients with no systemic or ocular problems that would interfere with postoperative visual acuity were included in this prospective study. Each patient had in-the-bag implantation of an AcrySof IOL in 1 eye and a MemoryLens in the fellow eye in a randomized fashion after uneventful phacoemulsification through a sutureless clear corneal incision.

Results: At 1 year (n = 32 patients), there was no significant difference between fellow eyes in postoperative best corrected visual acuity (BCVA) and contrast sensitivity. In the MemoryLens group, 10 eyes (31.3%) had PCO and 9 (28.1%), LEC migration. In the AcrySof group, no eye had PCO and 2 eyes (6.3%) had LEC migration (P <.001). At 3 years (n = 21 patients), 1 eye (4.7%) in the AcrySof group had PCO and 3 eyes (14.4%) had LEC migration without PCO. In the MemoryLens group, 1 eye (4.7%) had a clear posterior capsule, 11 eyes (52.4%) had LEC migration, and 9 eyes (42.9%) had PCO (P <.001). A neodymium:YAG capsulotomy was required in 4 eyes (19.0%) in the MemoryLens group but no eye in the AcrySof group. At 3 years, BCVA was lower in the MemoryLens group than in the AcrySof group (P <.05).

Conclusion: The 3 year clinical data of fellow eyes indicate that the AcrySof IOL causes less PCO than the MemoryLens.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Acrylates / adverse effects*
  • Aged
  • Biocompatible Materials / adverse effects*
  • Cataract / etiology*
  • Cataract / pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Laser Therapy
  • Lens Capsule, Crystalline / pathology*
  • Lens Implantation, Intraocular*
  • Lenses, Intraocular / adverse effects*
  • Male
  • Phacoemulsification
  • Polypropylenes / adverse effects*
  • Prognosis
  • Prospective Studies
  • Prosthesis Design
  • Refraction, Ocular
  • Reoperation
  • Visual Acuity


  • Acrylates
  • Biocompatible Materials
  • Polypropylenes