Bartonella henselae, B. quintana, and B. bacilliformis: historical pathogens of emerging significance

Microbes Infect. 2000 Aug;2(10):1193-205. doi: 10.1016/s1286-4579(00)01273-9.


Bartonella species were virtually unrecognized as modern pathogens of humans until the last decade. However, identification of Bartonella species as the agents of cat-scratch disease, bacillary angiomatosis, urban trench fever, and possible novel presentations of Carrion's disease has left little doubt of the emerging medical importance of this genus of organisms. The three primary human pathogenic bartonellae, Bartonella bacilliformis (Carrion's disease), B. henselae (cat-scratch disease), and B. quintana (trench fever), present noteworthy comparisons in the epidemiology, natural history, pathology, and host-microbe interaction that this review will briefly explore.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Animals
  • Bartonella / pathogenicity*
  • Bartonella Infections* / history
  • Bartonella Infections* / microbiology
  • Bartonella Infections* / transmission
  • Bartonella henselae / pathogenicity
  • Bartonella quintana / pathogenicity
  • Disease Reservoirs
  • History, 19th Century
  • History, 20th Century
  • Humans
  • Zoonoses* / history
  • Zoonoses* / microbiology
  • Zoonoses* / transmission