Evaluation of Etest for susceptibility testing of Mycobacterium tuberculosis

J Clin Microbiol. 2000 Oct;38(10):3834-6. doi: 10.1128/JCM.38.10.3834-3836.2000.

Abstract

The Etest method for susceptibility testing of Mycobacterium tuberculosis was compared to the agar proportion method using four first-line agents and two fluoroquinolones. Catergorical agreement between the methods was 100% for rifampin, ethambutol, streptomycin, and ofloxacin and 98% for isoniazid. Results were obtained in 6 to 10 days by Etest. The Etest method is suitable for testing the agents evaluated against M. tuberculosis.

Publication types

  • Comparative Study

MeSH terms

  • Agar
  • Anti-Infective Agents / pharmacology*
  • Antitubercular Agents / pharmacology*
  • Ciprofloxacin / pharmacology
  • Ethambutol / pharmacology
  • Humans
  • Isoniazid / pharmacology
  • Microbial Sensitivity Tests / methods*
  • Mycobacterium tuberculosis / drug effects*
  • Mycobacterium tuberculosis / isolation & purification
  • Ofloxacin / pharmacology
  • Rifampin / pharmacology
  • Streptomycin / pharmacology

Substances

  • Anti-Infective Agents
  • Antitubercular Agents
  • Ciprofloxacin
  • Ethambutol
  • Agar
  • Ofloxacin
  • Isoniazid
  • Rifampin
  • Streptomycin