Ankyrins

FEBS Lett. 2000 Sep 29;482(1-2):1-5. doi: 10.1016/s0014-5793(00)01924-4.

Abstract

This review is focused on ankyrin which is a protein linker between the integral membrane proteins and spectrin-based cytoskeleton. Structure and distribution of different ankyrin isoforms that are products of alternative-spliced genes are described. Interaction of ankyrins with various membranes is considered. Special attention is paid to ankyrin participation in signal transduction and in assembly of integral membrane proteins in specialized membrane domains.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Ankyrins / chemistry
  • Ankyrins / genetics
  • Ankyrins / metabolism*
  • Cytoskeletal Proteins / metabolism
  • Humans
  • Membrane Proteins / metabolism
  • Protein Isoforms / chemistry
  • Protein Isoforms / genetics
  • Protein Isoforms / metabolism

Substances

  • Ankyrins
  • Cytoskeletal Proteins
  • Membrane Proteins
  • Protein Isoforms