Ulcerative balanoposthitis of the foreskin as a manifestation of chronic lymphocytic leukemia: case report and review of the literature

Urology. 2000 Oct 1;56(4):669. doi: 10.1016/s0090-4295(00)00735-4.


Ulcerative lesions of the penis have many possible etiologies, including infectious, neoplastic, traumatic, drug-induced, and autoimmune. Although the most frequent neoplasm presenting as an ulcerative penile lesion is squamous cell carcinoma, it may rarely be a manifestation of other malignancies, including those of hematolymphoid origin. We report a case of ulcerative balanoposthitis as a manifestation of chronic lymphocytic leukemia. Chronic lymphocytic leukemia and other hematolymphoid malignancies should be considered in the large differential diagnosis of nonhealing penile ulcers.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Balanitis / etiology*
  • Balanitis / pathology*
  • Fatal Outcome
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / complications*
  • Male
  • Multiple Organ Failure
  • Penis / pathology
  • Skin Ulcer / etiology*
  • Skin Ulcer / pathology*