Gout attacks and lunar cycle

Med Hypotheses. 2000 Jul;55(1):24-5. doi: 10.1054/mehy.1999.0973.


The aim was to search for periodical fluctuations in daily occurrence of gout attacks during the synodic lunar cycle. 126 gout attacks were recorded between 1972 and 1994 at known calendar dates. The synodic plexogram, displaying the number of attacks for each day of the cycle, was processed by cosinor regression. A pronounced cycling was found, with highest peaks under the new and full moon (syzygigies). Thus, the maximal occurrence of attacks coincides with the peaking lunisolar tidal effect. Similar relation of attacks to synodic moon was seen in bronchial asthma of children, and a reciprocal one in paroxysmal tachyarrhythmia. Differing pathogenetic backgrounds of these diseases substantiate the observed differences in their putative reactions on the changing cosmogeophysical environment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Gout / physiopathology*
  • Humans
  • Male
  • Moon*
  • Periodicity*