Cutaneous melanoma in a patient with neurofibromatosis

Arch Dermatol. 1979 Jul;115(7):864-5.


Although neurofibromatosis and cutaneous melanoma are both diseases of neuroectodermal origin, reports of their association are rare. The case history of a patient with histologically documented neurofibromatosis and a nodular melanoma unrelated to a cafe-au-lait spot or congenital nevus is reported, and the literature reviewed. The appearance of only one patient with neurofibromatosis in a series of 900 patients with melanoma suggests that these diseases are probably not associated with greater frequency than that predicted by chance alone.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Male
  • Melanoma / complications*
  • Melanoma / pathology
  • Neurofibromatosis 1 / complications*
  • Neurofibromatosis 1 / pathology
  • Skin Neoplasms / pathology