Abstract
Great advances have been made in understanding the cause and molecular genesis of colorectal cancer. The disease can be prevented by a healthful diet and lifestyle or by resecting the precursor of most of these cancers, the advanced adenomatous polyp. Screening the average-risk population plus special surveillance for high-risk groups now is recommended by evidence-based guidelines. Surgery is highly curative for patients without distant metastases, and adjuvant therapy improves survival in selected patients with advanced cancers.
MeSH terms
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Adenomatous Polyps / surgery
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Colonic Neoplasms / etiology
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Colonic Neoplasms / genetics
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Colonic Neoplasms / prevention & control*
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Colonic Neoplasms / surgery
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Colonic Neoplasms / therapy
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Colonic Polyps / surgery
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Diet
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Evidence-Based Medicine
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Humans
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Life Style
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Mass Screening*
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Molecular Biology
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Neoadjuvant Therapy
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Population Surveillance
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Practice Guidelines as Topic
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Precancerous Conditions / surgery
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Rectal Neoplasms / etiology
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Rectal Neoplasms / genetics
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Rectal Neoplasms / prevention & control*
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Rectal Neoplasms / surgery
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Rectal Neoplasms / therapy
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Risk Factors