Potassium tert-butoxide catalyzed addition of carbonyl derivatives to styrenes

AL Rodriguez; T Bunlaksananusorn; P Knochel

doi:10.1021/ol000174l

Potassium tert-butoxide catalyzed addition of carbonyl derivatives to styrenes

Org Lett. 2000 Oct 19;2(21):3285-7. doi: 10.1021/ol000174l.

Authors

AL Rodriguez¹, T Bunlaksananusorn, P Knochel

Affiliation

¹ Ludwig-Maximilians-Universitat Munchen, Institut fur Organische Chemie, Butenandtstrasse 5-13, Haus F, 81377 Munchen, Germany.

PMID: 11029191
DOI: 10.1021/ol000174l

Abstract

A catalytic amount of t-BuOK in DMSO allows the addition of ketones or imines to styrenes at 40 degrees C in good to excellent yield. Nitriles add to styrenes in NMP or in DMSO at room temperature.