The relation between mitral annulus motion and ejection fraction: a nonlinear function

J Am Soc Echocardiogr. 2000 Oct;13(10):896-901. doi: 10.1067/mje.2000.107253.


In previous studies of the relation between mitral annulus motion (MAM) and left ventricular ejection fraction (EF), a linear relationship has been suggested. In this meta-analysis of 434 patients, we show that the relation is nonlinear and that a linear regression model overestimates EF in the lower range of MAM. The relation is better described by an S function and is influenced by age and heart size.

Publication types

  • Meta-Analysis
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Coronary Angiography
  • Humans
  • Linear Models
  • Middle Aged
  • Mitral Valve / diagnostic imaging*
  • Mitral Valve / physiopathology*
  • Radionuclide Angiography
  • Stroke Volume*
  • Ultrasonography