Early androgenetic alopecia as a marker of insulin resistance

Lancet. 2000 Sep 30;356(9236):1165-6. doi: 10.1016/S0140-6736(00)02763-X.


The previously proven association between androgenetic, alopecia and serious cardiovascular events raises a question of the common pathogenetic mechanism of these disorders. Our practice-based case-control study in men aged 19-50 years showed a strikingly increased risk of hyperinsulinaemia and insulin-resistance-associated disorders such as obesity, hypertension, and dyslipidemia in men with early onset of alopecia (<35), compared with age-matched controls. This finding supports the hypothesis that early androgenetic alopecia could be a clinical marker of insulin resistance.

Publication types

  • Letter

MeSH terms

  • Adult
  • Alopecia / epidemiology
  • Alopecia / etiology*
  • Alopecia / genetics
  • Antihypertensive Agents / adverse effects
  • Biomarkers
  • Body Mass Index
  • Case-Control Studies
  • Finland / epidemiology
  • Humans
  • Hypoglycemic Agents / adverse effects
  • Insulin Resistance*
  • Male
  • Middle Aged
  • Risk Factors


  • Antihypertensive Agents
  • Biomarkers
  • Hypoglycemic Agents