Visual outcome after surgical removal of choroidal neovascularization in pediatric patients

Arch Ophthalmol. 2000 Oct;118(10):1373-8. doi: 10.1001/archopht.118.10.1373.


Objective: To assess the visual outcome after surgical removal of choroidal neovascularization (CNV) in pediatric patients.

Methods: A retrospective, noncomparative, consecutive case series of 17 eyes undergoing surgical removal of CNV of various causes in patients aged 18 years and younger.

Results: The cause of the CNV was presumed ocular histoplasmosis syndrome in 11 eyes, idiopathic in 3, and optic nerve coloboma, ocular toxoplasmosis, and trauma in 1 eye each. Two eyes had CNV within 100 microm of the center of the foveal avascular zone (juxtafoveal CNV) and 1 eye had peripapillary CNV, while 14 eyes had CNV beneath the geometric center of the foveal avascular zone (subfoveal CNV). In eyes with subfoveal CNV, median preoperative Snellen visual acuity was 20/200 (range, 20/80-3/200). With a median follow-up of 27 months (range, 6-45 months), median final visual acuity was 20/50 (range, 20/20-2/200); 10 (72%) had improvement of 2 or more Snellen lines after surgery, and 6 eyes (43%) had final visual acuity of 20/40 or better. In 3 eyes with juxtafoveal CNV or peripapillary CNV, all eyes had improvement of 4 or more Snellen lines. Postoperative recurrent CNV developed in 6 (35%) of 17 patients; 2 of the eyes underwent a second vitrectomy and 4 received laser treatment for the recurrences.

Conclusions: Pediatric patients may have good recovery of vision after surgical removal of CNV, and the removal of these membranes may be a viable alternative to laser photocoagulation in pediatric patients.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Child
  • Choroidal Neovascularization / etiology
  • Choroidal Neovascularization / physiopathology
  • Choroidal Neovascularization / surgery*
  • Eye Diseases / complications
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fundus Oculi
  • Humans
  • Laser Coagulation
  • Male
  • Recurrence
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity*
  • Vitrectomy