Management of severe blistering disorders

Abstract

Sufferers of the genetically determined blistering skin condition epidermolysis bullosa require specialized management throughout life. This management must begin shortly after birth in order to minimize additional skin damage, some of which may lead to permanent disability. Even the gentle handling practised routinely in neonatal units will result in painful blistering and loss of skin in the severely affected infant. Procedures such as cannulation, screening and monitoring must be modified if unnecessary trauma is to be avoided.