Penetrating keratoplasty and glaucoma

Surv Ophthalmol. Sep-Oct 2000;45(2):91-105. doi: 10.1016/s0039-6257(00)00141-7.

Abstract

Glaucoma remains the leading cause of blindness after penetrating keratoplasty. Post-keratoplasty glaucoma was originally described in 1969, and its management is still controversial. Recent developments in management include newer classes of drugs, surgical procedures, such as trabeculectomy with mitomycin-C, implantation of glaucoma drainage devices, and cyclodestructive procedures with Nd: YAG and diode lasers. However, the risk of graft failure continues to be high with all surgical procedures.

Publication types

  • Review

MeSH terms

  • Alkylating Agents / administration & dosage
  • Diagnosis, Differential
  • Glaucoma / diagnosis
  • Glaucoma / epidemiology
  • Glaucoma / etiology*
  • Glaucoma / therapy
  • Glaucoma Drainage Implants
  • Humans
  • Incidence
  • Intraocular Pressure / physiology
  • Keratoplasty, Penetrating / adverse effects*
  • Mitomycin / administration & dosage
  • Ophthalmic Solutions
  • Prognosis
  • Refractive Surgical Procedures
  • Risk Factors
  • Trabeculectomy

Substances

  • Alkylating Agents
  • Ophthalmic Solutions
  • Mitomycin