Abstract
The concentrations of norepinephrine, dopamine-beta-hydroxylase, dopamine, tyrosine hydroxylase, phenylethanolamine-N-methyltransferase, serotonin, tryptophan hydroxylase, histamine, glutamic acid decarboxylase, and choline acetyltransferase were determined in selected hypothalamic nuclei and in the median eminence after deafferentation of the medial basal hypothalamus. Norepinephrine and dopamine-beta-hydroxylase fell markedly while dopamine and tyrosine hydroxylase did not. Serotonin also decreased in all regions studied; histamine decreased in none. Choline acetyltransferase, phenylethanolamine-N-methyltransferase, and glutamic acid decarboxylase declined in some areas, but not in others.
MeSH terms
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Animals
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Choline O-Acetyltransferase / metabolism
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Dopamine / metabolism
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Dopamine beta-Hydroxylase / metabolism
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Female
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Glutamate Decarboxylase / metabolism
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Histamine / metabolism
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Hypothalamus / metabolism
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Hypothalamus / physiology*
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Neurons, Afferent / physiology
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Neurotransmitter Agents / metabolism*
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Norepinephrine / metabolism
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Phenylethanolamine N-Methyltransferase / metabolism
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Rats
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Serotonin / metabolism
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Tryptophan Hydroxylase / metabolism
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Tyrosine 3-Monooxygenase / metabolism
Substances
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Neurotransmitter Agents
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Serotonin
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Histamine
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Tyrosine 3-Monooxygenase
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Tryptophan Hydroxylase
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Dopamine beta-Hydroxylase
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Phenylethanolamine N-Methyltransferase
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Choline O-Acetyltransferase
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Glutamate Decarboxylase
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Dopamine
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Norepinephrine