Scleromyxoedema-like cutaneous diseases in renal-dialysis patients

Lancet. 2000 Sep 16;356(9234):1000-1. doi: 10.1016/S0140-6736(00)02694-5.


15 renal dialysis patients have been identified with a skin condition characterised by thickening and hardening of the skin of the extremities and an increase in dermal fibroblast-like cells associated with collagen remodelling and mucin deposition. The disease closely resembles scleromyxoedema, yet has significant enough clinical and histopathological differences to warrant its designation as a new clinicopathological entity.

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Kidney Transplantation / adverse effects
  • Male
  • Middle Aged
  • Renal Dialysis / adverse effects*
  • Scleroderma, Localized / epidemiology
  • Scleroderma, Localized / etiology*
  • Scleroderma, Localized / pathology
  • United States / epidemiology