Prader-Willi psychiatric syndrome and Velo-Cardio-Facial psychiatric syndrome

Genet Couns. 2000;11(3):205-13.


Prader-Willi psychiatric syndrome and Velo-Cardio-Facial psychiatric syndrome: Similar to the studies on behavioural phenotypes, it is suggested to more rigorously promote the investigation of psychopathological phenotypes. The psychopathological profile in patients with Prader-Willi Syndrome (PWS) or Velo-Cardio-Facial Syndrome (VCFS) appears to be not classifiable within the current nosological systems. On a descriptive level, PWS-psychotic states show similarities with the cycloid psychoses, but VCFS psychosis does not. It is therefore advocated to adopt the notion of a brain-structure phenotype as well as that of a syndrome-specific psychiatric disorder.

Publication types

  • Case Reports
  • Comparative Study
  • Review

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Face / abnormalities*
  • Female
  • Heart Defects, Congenital / genetics*
  • Humans
  • Male
  • Mental Disorders / genetics*
  • Mental Disorders / psychology*
  • Palate, Soft / abnormalities*
  • Prader-Willi Syndrome / diagnosis
  • Prader-Willi Syndrome / genetics*
  • Prader-Willi Syndrome / psychology*
  • Syndrome