Detection of determinism within time series of irregular burst firing from the injured sensory neuron

Neuroreport. 2000 Sep 28;11(14):3295-8. doi: 10.1097/00001756-200009280-00049.


Irregular burst firing is spontaneously generated by rat dorsal root ganglion neuron after chronic compression. To investigate the time series of burst firing, we recorded interspike intervals (ISIs) of single-unit firing in vitro and processed the ISIs to obtain interevent intervals (IEIs). Then, two non-linear methods were applied to detect deterministic dynamic behaviors in IEI series. No evidence for the existence of determinism was found with non-linear prediction method. Using unstable periodic orbit identification method, significant period-1 orbits were identified in all 10 data, period-2 orbits in eight, and period-3 orbits in six. The results indicate that there exist significant deterministic behaviors in the time series of irregular burst firing from the injured sensory neuron.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology*
  • Animals
  • Female
  • Ganglia, Spinal / injuries
  • Ganglia, Spinal / pathology
  • Ganglia, Spinal / physiopathology*
  • Male
  • Nerve Crush / adverse effects*
  • Neurons, Afferent / cytology
  • Neurons, Afferent / physiology*
  • Nonlinear Dynamics
  • Rats
  • Rats, Sprague-Dawley
  • Time Factors