Job strain, Type A behavior pattern, and the prevalence of coronary atherosclerosis in Japanese working men

J Psychosom Res. 2000 Jul;49(1):77-83. doi: 10.1016/s0022-3999(00)00145-8.


Objective: To examine the relation of type A behavior pattern and job strain to angiographically documented coronary stenosis.

Methods: Subjects were 197 male Japanese patients with a full-time job. A questionnaire-based interview elicited psychosocial and other factors. Type A behavior pattern was measured by 12 questions, and job strain by the method of Karasek. Significant coronary stenosis was defined when a 75% or greater luminal narrowing occurred at one or more major coronary arteries or when a 50% or greater narrowing occurred at the left main artery. Logistic regression analysis was used to calculate odds ratio (OR) and 95% confidence interval (CI) with adjustment for traditional coronary risk factors and job type.

Results: Type A behavior pattern was related to a statistically non-significant lower prevalence of the coronary stenosis especially in the absence of job strain (adjusted OR 0.6, 95% CI 0.3-1.2). Job strain was non-significantly associated with a modestly increased prevalence of coronary stenosis (OR 1.7, 95% CI 0.6-5.2).

Conclusion: These findings suggest that both the behavioral pattern and psychosocial work environment may be related to coronary artery stenosis.

MeSH terms

  • Adult
  • Coronary Angiography
  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / psychology*
  • Cross-Sectional Studies
  • Humans
  • Incidence
  • Japan / epidemiology
  • Job Satisfaction*
  • Male
  • Middle Aged
  • Risk Factors
  • Stress, Psychological / complications*
  • Type A Personality*