Ocular findings in aplastic anemia

Ophthalmologica. 2000;214(6):399-402. doi: 10.1159/000027532.


Objective: To analyze the ocular findings in aplastic anemia.

Design: Eighteen patients with aplastic anemia were examined.

Results: Ocular findings included cotton wool spots (38%), nerve fiber layer or preretinal hemorrhages (67%), vitreous hemorrhages (13%), a picture resembling central retinal vein occlusion (13%) and optic disk edema (6%). Preretinal hemorrhages were the presenting sign of aplastic anemia in 2 patients (13%).

Conclusions: A blood profile is needed in patients with unexplained retinal hemorrhages. Patients with aplastic anemia need to avoid ocular massage and Valsalva maneuvers to decrease ocular morbidity.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anemia, Aplastic / diagnosis*
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Fundus Oculi
  • Humans
  • Male
  • Middle Aged
  • Papilledema / diagnosis*
  • Retinal Diseases / diagnosis*
  • Visual Acuity
  • Vitreous Hemorrhage / diagnosis*