The enigmatic inflammatory pseudotumours: the current state of our understanding, or misunderstanding

J Pathol. 2000 Nov;192(3):277-9. doi: 10.1002/1096-9896(200011)192:3<277::AID-PATH749>3.0.CO;2-E.


The inflammatory pseudotumour is a bona fide tumour in the sense of a mass lesion, which is known to present in virtually every anatomic region and organ from the central nervous system to the gastrointestinal tract. A fundamental question about pathogenesis is whether the inflammatory pseudotumour is a pseudo-or true neoplasm. There is evidence to support the argument that some of these fibroinflammatory masses are infection-associated and are often characterized by a proliferation of spindled histiocytes and/or dendritic cells, in contrast to a myofibroblastic proliferation in the other inflammatory pseudotumour, also known as the inflammatory myofibroblastic tumour.

Publication types

  • Comment
  • Editorial

MeSH terms

  • Bacterial Infections / complications
  • Granuloma, Plasma Cell / etiology*
  • Granuloma, Plasma Cell / pathology
  • Humans
  • Precancerous Conditions / etiology*
  • Precancerous Conditions / pathology
  • Virus Diseases / complications