Mullerian adenosarcoma of the uterus: case report and review of literature

Eur J Gynaecol Oncol. 2000;21(4):387-90.

Abstract

Mullerian adenosarcoma--a variant of mullerian mixed mesodermal tumor of the uterus--is typically composed of benign but sometimes mildly atypical glandular epithelial elements admixed with malignant sarcomatous stroma. This rare tumor, which accounts for only about 8% of all uterine sarcomas, usually originates in the endometrium and grows as a polypoid mass within the endometrial cavity. The most prevailing presenting symptom is abnormal vaginal bleeding and the most common finding is a polypoid mass protruding through a dilated cervical canal. The case of a woman, who at age 62 presented with symptoms and signs of acute pelvic inflammatory disease and on vaginal examination an infected mullerian adenosarcoma protruding through a dilated cervical canal was discovered, is reported. Treatment consisted of extensive antibiotic treatment and surgery comprised of total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by postoperative adjuvant pelvic radiotherapy. One year later, the patient is alive with no evidence of disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenosarcoma / pathology
  • Adenosarcoma / radiotherapy
  • Adenosarcoma / surgery*
  • Female
  • Humans
  • Hysterectomy
  • Middle Aged
  • Mixed Tumor, Mullerian / pathology
  • Mixed Tumor, Mullerian / radiotherapy
  • Mixed Tumor, Mullerian / surgery*
  • Ovariectomy
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / radiotherapy
  • Uterine Neoplasms / surgery*