Treatment of severe complicated Kawasaki disease with oral prednisolone and aspirin

J Pediatr. 2000 Nov;137(5):723-6. doi: 10.1067/mpd.2000.108444.


We report on 7 patients with severe, complicated Kawasaki disease treated with oral prednisolone, after apparently unsuccessful intravenous immunoglobulin treatment. An additional eighth patient was a Jehovah's Witness, who was given steroid and aspirin as first-line treatment. These findings support a beneficial role for steroids in intravenous immunoglobulin-resistant Kawasaki disease.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use*
  • Aspirin / therapeutic use*
  • Child
  • Child, Preschool
  • Drug Therapy, Combination
  • Glucocorticoids / therapeutic use*
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Infant
  • Male
  • Mucocutaneous Lymph Node Syndrome / drug therapy*
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Prednisolone / therapeutic use*
  • Treatment Failure


  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Immunoglobulins, Intravenous
  • Platelet Aggregation Inhibitors
  • Prednisolone
  • Aspirin