Synthesis of the potent antimalarials calothrixin A and B

Org Lett. 2000 Nov 16;2(23):3735-7. doi: 10.1021/ol006649q.

Abstract

A concise synthesis of calothrixins A (1) and B (2) that confirms their assigned structures and affords straightforward synthetic access to them is reported.

MeSH terms

  • Antimalarials / chemical synthesis*
  • Crystallography, X-Ray
  • Indole Alkaloids
  • Indoles / chemical synthesis*

Substances

  • Antimalarials
  • Indole Alkaloids
  • Indoles
  • calothrixin A
  • calothrixin B