Dietary vitamin E, IgE concentrations, and atopy

Lancet. 2000 Nov 4;356(9241):1573-4. doi: 10.1016/S0140-6736(00)03132-9.


Vitamin E inhibits IgE responses to allergic stimuli in animals. We investigated the relation between dietary vitamin E intake and serum IgE concentrations and atopy, measured as allergen skin sensitisation, in a random sample of 2633 adults. Higher concentrations of vitamin E intake were associated with lower serum IgE concentrations and a lower frequency of allergen sensitisation. These findings may explain the beneficial effect of dietary vitamin E on the incidence of asthma.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Animals
  • Diet
  • Female
  • Humans
  • Hypersensitivity, Immediate / prevention & control*
  • Immunoglobulin E / blood*
  • Logistic Models
  • Male
  • Middle Aged
  • Skin Tests
  • Smoking / adverse effects
  • Vitamin E / administration & dosage
  • Vitamin E / therapeutic use*


  • Vitamin E
  • Immunoglobulin E