Successful uterine steroid therapy in a case with a history of ten miscarriages

Am J Reprod Immunol. 2000 Oct;44(4):253-5. doi: 10.1111/j.8755-8920.2000.440411.x.

Abstract

A woman experienced ten unexplained first trimester miscarriages. Uterine steroid therapy was performed just before her 11th pregnancy. Prednisolone was inserted into the uteral cavity before ovulation and her 11th pregnancy resulted in success. Our experience in this case confirms the potential usefulness of this treatment for patients with unexplained recurrent miscarriages.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Habitual / drug therapy*
  • Abortion, Habitual / genetics
  • Abortion, Habitual / immunology
  • Adult
  • Female
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Infant, Newborn
  • Killer Cells, Natural / immunology
  • Male
  • Methylprednisolone / administration & dosage*
  • Pregnancy
  • Translocation, Genetic
  • Uterus / drug effects
  • Uterus / immunology

Substances

  • Immunosuppressive Agents
  • Methylprednisolone