Placement of endosseous implants in patients with oral epidermolysis bullosa

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Nov;90(5):587-90. doi: 10.1067/moe.2000.110438.


Objective: To evaluate the feasibility of placing endosseous implants in patients with recessive dystrophic epidermolysis bullosa. This article reports on 4 patients subjected to follow-up.

Study design: Implants were placed in 4 cases. All patients have marked oral involvement, with devastating alterations in the soft and hard tissues in all cases.

Results: A total of 15 implants (7 maxillary, 8 mandibular) were placed. All implants integrated successfully and have been restored. The average follow-up from implant placement was 2.5 years (range, 1-4).

Conclusions: Our preliminary findings suggest that endosseous implants can be successfully placed and can provide support for prosthetic restoration in patients with recessive dystrophic epidermolysis bullosa.

MeSH terms

  • Adult
  • Dental Care for Chronically Ill*
  • Dental Implantation, Endosseous / methods*
  • Dental Prosthesis, Implant-Supported
  • Denture, Overlay
  • Epidermolysis Bullosa Dystrophica* / genetics
  • Epidermolysis Bullosa Dystrophica* / pathology
  • Female
  • Genes, Recessive
  • Humans
  • Jaw, Edentulous / rehabilitation*
  • Jaw, Edentulous / surgery
  • Male
  • Mouth Diseases* / genetics
  • Mouth Diseases* / pathology
  • Mouth Mucosa / pathology
  • Prospective Studies
  • Treatment Outcome