Clinical features characterizing young-onset and intermediate-onset schizophrenia

J Neuropsychiatry Clin Neurosci. 2000 Fall;12(4):502-5. doi: 10.1176/jnp.12.4.502.


Late-onset schizophrenia has been noted to have distinct clinical characteristics. The authors compared symptom characteristics between early- and intermediate-onset patients (N = 259) to determine whether clinical features distinguished differences within younger populations. On global measures of psychotic, disorganized, and negative symptoms, early-onset patients had greater disorganized and negative symptoms but did not differ in hallucinations and delusions. The dichotomy of early vs. late onset may extend to a younger population, reflecting a more continuous influence.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age Factors
  • Age of Onset*
  • Chronic Disease
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Psychiatric Status Rating Scales
  • Regression Analysis
  • Schizophrenia / classification
  • Schizophrenia / diagnosis*
  • Schizophrenic Psychology*
  • Severity of Illness Index