Renal vein thrombosis: a 10-year review

J Pediatr Surg. 2000 Nov;35(11):1540-2. doi: 10.1053/jpsu.2000.18302.


Purpose: Renal vein thrombosis (RVT) is a rare cause for pediatric surgical consultation. The purpose of this study is to review the Montreal experience in the 1990s with RVT.

Methods: A retrospective chart review was conducted from 1990 through 1999.

Results: Twenty-three cases were identified by Duplex ultrasound scan. Mean length of follow-up was 42 months. Eighty-three percent (83%) of cases were diagnosed within the first month of life. In utero thrombosis was suspected in 22% and was associated with caval thrombosis and factor V Leiden. Known risk factors were present in 87%. The "diagnostic triad" of flank mass, gross hematuria, and thrombocytopenia was present in only 13% at the time of diagnosis. Long-term renal function impairment was detected in 100% of those who did not receive heparin, and in 33% of those who did receive heparin. No patient required dialysis. One patient required nephrectomy for recurrent pyelonephritis.

Conclusions: RVT occurs more commonly than anticipated. Because the "classic" triad of signs usually is absent at presentation, the presence of either a flank mass, hematuria, or thrombocytopenia in a patient with risk factors should prompt investigation for RVT. Factor V Leiden is a risk factor for in utero RVT. Anticoagulation improves renal outcome. Patients with RVT require long-term follow-up.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Age Distribution
  • Anticoagulants / administration & dosage
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Infant, Newborn
  • Male
  • Quebec / epidemiology
  • Renal Veins*
  • Retrospective Studies
  • Risk Factors
  • Sex Distribution
  • Survival Rate
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / drug therapy
  • Venous Thrombosis / epidemiology*


  • Anticoagulants