Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance

Antimicrob Agents Chemother. 2000 Dec;44(12):3249-56. doi: 10.1128/AAC.44.12.3249-3256.2000.

Authors

L P Kotra¹, J Haddad, S Mobashery

Affiliation

¹ Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

No abstract available

Publication types

Review

MeSH terms

Aminoglycosides
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects*
Bacteria / enzymology
Bacteria / metabolism
Carbohydrate Sequence
Drug Design
Drug Resistance, Microbial / physiology
Models, Molecular
Molecular Sequence Data
RNA, Ribosomal, 16S / metabolism
Structure-Activity Relationship

Substances

Aminoglycosides
Anti-Bacterial Agents
RNA, Ribosomal, 16S