Tremor and myoclonus heralding Hashimoto's encephalopathy

J Pediatr Endocrinol Metab. Sep-Oct 2000;13(8):1137-41. doi: 10.1515/jpem.2000.13.8.1137.


We report the clinical laboratory, electroencephalography (EEG), magnetic resonance imaging (MRI) and single photon emission computerized tomography (SPECT) findings in a 15 year-old euthyroid girl with autoimmune thyroiditis and encephalopathy. She had stupor, coma and generalized tonic clonic seizure preceded by tremor and myoclonus with a previous misdiagnosis of epilepsy and encephalitis. Response to steroid after the 3rd relapse was excellent. Another four children in the literature are also discussed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Brain Diseases / diagnosis
  • Brain Diseases / etiology*
  • Electroencephalography
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Magnetic Resonance Imaging
  • Methylprednisolone / therapeutic use
  • Myoclonus / etiology*
  • Thyroiditis, Autoimmune / complications*
  • Thyroiditis, Autoimmune / drug therapy
  • Tomography, Emission-Computed, Single-Photon
  • Tremor / etiology*


  • Glucocorticoids
  • Methylprednisolone