Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

J Clin Invest. 2000 Nov;106(10):1197-202. doi: 10.1172/JCI11631.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Carcinoma, Lewis Lung / drug therapy*
  • Catalysis
  • Enzyme Stability
  • Hepatitis, Chronic / drug therapy*
  • Humans
  • Lung Neoplasms / drug therapy*
  • RNA Stability
  • RNA, Catalytic / chemical synthesis
  • RNA, Catalytic / therapeutic use*
  • Ribonucleases* / metabolism

Substances

  • Angiozyme
  • RNA, Catalytic
  • Ribonucleases