Natural vitamins may be superior to synthetic ones

Med Hypotheses. 2000 Dec;55(6):461-9. doi: 10.1054/mehy.2000.1090.


There appears to be a tendency to label those who profess that natural vitamins are better than synthetic ones as quacks. This broad brush label may be stifling legitimate nutrition research. This paper describes physiochemical differences between certain natural and synthetic vitamins, proven clinical advantages of natural vitamins, and some of the effects this labeling may lead to. It concludes that lessons of history as well as modern science support the view that natural vitamins are nutritionally superior to synthetic ones.

MeSH terms

  • Biological Availability
  • Biological Factors / chemistry*
  • Biological Factors / pharmacokinetics
  • Food Handling
  • Vitamins / chemistry*
  • Vitamins / pharmacokinetics


  • Biological Factors
  • Vitamins