NKT cells: facts, functions and fallacies
- PMID: 11094262
- DOI: 10.1016/s0167-5699(00)01735-7
NKT cells: facts, functions and fallacies
Abstract
The proposed roles of NK1.1(+) T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, whenever possible, to compare what is known about NKT-cell subsets.
Similar articles
-
Regulation of tumor immunity: the role of NKT cells.Expert Opin Biol Ther. 2008 Jun;8(6):725-34. doi: 10.1517/14712598.8.6.725. Expert Opin Biol Ther. 2008. PMID: 18476784 Review.
-
alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles.Nat Rev Immunol. 2005 Jan;5(1):31-42. doi: 10.1038/nri1531. Nat Rev Immunol. 2005. PMID: 15630427 Review.
-
Control of NKT cell differentiation by tissue-specific microenvironments.J Immunol. 2003 Dec 1;171(11):5913-20. doi: 10.4049/jimmunol.171.11.5913. J Immunol. 2003. PMID: 14634102
-
Immunoregulation of autoimmunity by natural killer T cells.Hum Immunol. 2005 Dec;66(12):1193-202. doi: 10.1016/j.humimm.2006.02.020. Epub 2006 Mar 31. Hum Immunol. 2005. PMID: 16690406 Review.
-
Tissue-specific expansion of NKT and CD5+B cells at the onset of autoimmune disease in (NZBxNZW)F1 mice.Eur J Immunol. 2002 Sep;32(9):2551-61. doi: 10.1002/1521-4141(200209)32:9<2551::AID-IMMU2551>3.0.CO;2-C. Eur J Immunol. 2002. PMID: 12207339
Cited by
-
Oral N-acetylcysteine decreases IFN-γ production and ameliorates ischemia-reperfusion injury in steatotic livers.Front Immunol. 2022 Sep 5;13:898799. doi: 10.3389/fimmu.2022.898799. eCollection 2022. Front Immunol. 2022. PMID: 36148239 Free PMC article.
-
The vitamin d receptor and T cell function.Front Immunol. 2013 Jun 18;4:148. doi: 10.3389/fimmu.2013.00148. eCollection 2013. Front Immunol. 2013. PMID: 23785369 Free PMC article.
-
Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection.PLoS One. 2012;7(3):e33413. doi: 10.1371/journal.pone.0033413. Epub 2012 Mar 22. PLoS One. 2012. PMID: 22457760 Free PMC article.
-
Characterization of the early stages of thymic NKT cell development.J Exp Med. 2005 Aug 15;202(4):485-92. doi: 10.1084/jem.20050456. Epub 2005 Aug 8. J Exp Med. 2005. PMID: 16087715 Free PMC article.
-
Natural killer T cells and rheumatoid arthritis: friend or foe?Arthritis Res Ther. 2005;7(2):88-9. doi: 10.1186/ar1714. Epub 2005 Feb 14. Arthritis Res Ther. 2005. PMID: 15743495 Free PMC article. Review. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
