Further evidence for low serum cholesterol and suicidal behaviour

J Affect Disord. 2000 Dec;61(1-2):69-71. doi: 10.1016/s0165-0327(99)00198-6.


Objective: To examine for a relationship between serum cholesterol and suicidal behavior.

Methods: Patients admitted after an overdose (N=120) were compared with controls (N=120) for their serum cholesterol levels.

Results: Patients who had overdosed had significantly lower serum cholesterol levels than controls (mean+/-S.D. 171+/-31 vs. 196+/-30 mg/dl, P<0.0001).

Conclusion: These results add to a grouping literature reporting that low serum cholesterol is associated with suicidal behavior.

MeSH terms

  • Adult
  • Cholesterol / blood*
  • Depressive Disorder, Major / diagnosis
  • Depressive Disorder, Major / psychology
  • Female
  • Humans
  • Male
  • Psychiatric Status Rating Scales
  • Suicide, Attempted / psychology*
  • Suicide, Attempted / statistics & numerical data


  • Cholesterol