Pathogenesis of Proteus mirabilis urinary tract infection

Microbes Infect. 2000 Oct;2(12):1497-505. doi: 10.1016/s1286-4579(00)01304-6.

Abstract

Proteus mirabilis is a causative agent of cystitis and pyelonephritis primarily in individuals with indwelling catheters or structural abnormalities of the urinary tract. The organism produces a variety of unique virulence factors that contribute to its pathogenicity and persistence in the human host.

Publication types

  • Review

MeSH terms

  • Amidohydrolases / metabolism
  • Female
  • Humans
  • Immunoglobulin A / metabolism
  • Iron / metabolism
  • Male
  • Metalloendopeptidases / physiology
  • Proteus Infections / immunology
  • Proteus Infections / metabolism
  • Proteus Infections / microbiology*
  • Proteus mirabilis / metabolism
  • Proteus mirabilis / pathogenicity*
  • Pyelonephritis / metabolism
  • Pyelonephritis / microbiology
  • Urinary Bladder / microbiology
  • Urinary Tract Infections / immunology
  • Urinary Tract Infections / metabolism
  • Urinary Tract Infections / microbiology*

Substances

  • Immunoglobulin A
  • Iron
  • Metalloendopeptidases
  • serralysin
  • Amidohydrolases