The transcriptome of Arabidopsis thaliana during systemic acquired resistance

Nat Genet. 2000 Dec;26(4):403-10. doi: 10.1038/82521.

Abstract

Infected plants undergo transcriptional reprogramming during initiation of both local defence and systemic acquired resistance (SAR). We monitored gene-expression changes in Arabidopsis thaliana under 14 different SAR-inducing or SAR-repressing conditions using a DNA microarray representing approximately 25-30% of all A. thaliana genes. We derived groups of genes with common regulation patterns, or regulons. The regulon containing PR-1, a reliable marker gene for SAR in A. thaliana, contains known PR genes and novel genes likely to function during SAR and disease resistance. We identified a common promoter element in genes of this regulon that binds members of a plant-specific transcription factor family. Our results extend expression profiling to definition of regulatory networks and gene discovery in plants.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / metabolism
  • Arabidopsis / microbiology
  • Cluster Analysis
  • Gene Expression Regulation, Plant
  • Genes, Plant
  • Oligonucleotide Array Sequence Analysis
  • Oomycetes / parasitology
  • Plant Diseases / genetics
  • Plant Diseases / microbiology
  • Promoter Regions, Genetic
  • Regulon
  • Transcription Factors / genetics
  • Transcription Factors / metabolism
  • Transcription, Genetic

Substances

  • Transcription Factors