Hypoglycemic sensorimotor polyneuropathy associated with insulinoma

Muscle Nerve. 2000 Dec;23(12):1891-4. doi: 10.1002/1097-4598(200012)23:12<1891::aid-mus17>3.0.co;2-y.

Abstract

Hypoglycemia-induced peripheral neuropathy due to insulinoma is unusual and, as far as we know, has previously been reported in only 34 patients. In this case report, we describe the clinical features, electrophysiological features, and pathological findings in a 37-year-old patient with polyneuropathy from repeated hypoglycemic episodes over a 9-year period that related to an insulinoma. The literature is discussed. The reported case is of special interest because the peripheral neuropathy led to the correct diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Electrophysiology
  • Female
  • Humans
  • Hypoglycemia / etiology*
  • Insulinoma / complications
  • Insulinoma / diagnosis*
  • Insulinoma / physiopathology
  • Insulinoma / surgery
  • Motor Neurons / physiology
  • Neural Conduction
  • Neurons, Afferent / physiology
  • Pancreatic Neoplasms / complications
  • Pancreatic Neoplasms / diagnosis*
  • Pancreatic Neoplasms / physiopathology
  • Pancreatic Neoplasms / surgery
  • Peripheral Nervous System Diseases / etiology*
  • Peripheral Nervous System Diseases / physiopathology