Protein structure modeling for structural genomics

Nat Struct Biol. 2000 Nov;7 Suppl:986-90. doi: 10.1038/80776.


The shapes of most protein sequences will be modeled based on their similarity to experimentally determined protein structures. The current role, limitations, challenges and prospects for protein structure modeling (using information about genes and genomes) are discussed in the context of structural genomics.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Computer Simulation*
  • Computers
  • Databases as Topic
  • Genomics / methods*
  • Models, Molecular*
  • Protein Conformation
  • Proteins / chemistry*
  • Proteins / genetics


  • Proteins